TY - JOUR
T1 - Noninvasive mapping of ventricular activation in patients with transplanted hearts
AU - Desouza, Kavit A.
AU - Joseph, Susan M.
AU - Cuculich, Phillip S.
AU - Ewald, Gregory A.
AU - Rudy, Yoram
N1 - Funding Information:
Funding: Y.R. is the Fred Saigh Distinguished Professor at Washington University in St Louis. This study was supported by Grants 1UL1 RR024992-01 , 1TL1 RR024995-01 and 1KL2 RR 024994-01 from the National Center for Research Resources (NCRR) of the NIH .
PY - 2013/11
Y1 - 2013/11
N2 - This is the first reported study of ventricular activation patterns after cardiac transplantation, using electrocardiographic imaging (ECGI), a noninvasive method for electrophysiologic mapping. This study of ten patients reveals that transplanted hearts have unique ventricular activation patterns in sinus rhythm, activating early in the epicardial aspect of the anterior or inferior septum, with intact right and left bundle branch conduction. They have late activation with slowing of conduction near the right ventricular (RV) basal free wall, causing a mild QRS prolongation and an rSr' pattern in lead V1 of the ECG. PVCs arise from both endocardial and epicardial locations in both ventricles.
AB - This is the first reported study of ventricular activation patterns after cardiac transplantation, using electrocardiographic imaging (ECGI), a noninvasive method for electrophysiologic mapping. This study of ten patients reveals that transplanted hearts have unique ventricular activation patterns in sinus rhythm, activating early in the epicardial aspect of the anterior or inferior septum, with intact right and left bundle branch conduction. They have late activation with slowing of conduction near the right ventricular (RV) basal free wall, causing a mild QRS prolongation and an rSr' pattern in lead V1 of the ECG. PVCs arise from both endocardial and epicardial locations in both ventricles.
KW - Cardiac transplantation
KW - Conduction
KW - ECGI
KW - Electrocardiographic imaging
KW - Premature ventricular complexes
KW - Right ventricle
UR - http://www.scopus.com/inward/record.url?scp=84886951488&partnerID=8YFLogxK
U2 - 10.1016/j.jelectrocard.2013.05.005
DO - 10.1016/j.jelectrocard.2013.05.005
M3 - Article
C2 - 23773656
AN - SCOPUS:84886951488
SN - 0022-0736
VL - 46
SP - 698
EP - 701
JO - Journal of Electrocardiology
JF - Journal of Electrocardiology
IS - 6
ER -