TY - JOUR
T1 - Noninvasive estimation of left atrial pressure in patients with congestive heart failure and mitral regurgitation by Doppler echocardiography
AU - Gorcsan, John
AU - Snow, Frank R.
AU - Paulsen, Walter
AU - Nixon, J. V.
N1 - Funding Information:
From the Divisions versity of Pittsburgh. Supported in part by National Research Service Awards HE-07537 HL-07.580, National Heart, Lung, and Blood Institute, Bethesda. for publication April 30, 1990; accepted Aug. 20, 1990. Reprint requests: J. V. Nixon. MD, Division of Cardiology. Medical of Virginia. MCV Box 128, Richmond. VA 23298.
PY - 1991/3
Y1 - 1991/3
N2 - A completely noninvasive method for estimating left atrial pressure in patients with congestive heart failure and mitral regurgitation has been devised with the use of continuous-wave Doppler echocardiography and brachial sphygmomanometry. Of 46 patients studied with mitral regurgitation, 35 (76%) had jets with distinct Doppler spectral envelopes recorded. The peak ventriculoatrial gradient was obtained by measuring peak mitral regurgitant velocity in systole and using the modified Bernoulli equation. This gradient was then subtracted from peak brachial systolic blood pressure, an estimate of left ventricular systolic pressure, to yield left atrial pressure (left atrial pressure = systolic blood pressure - mitral regurgitant pressure gradient). Noninvasive estimates of left atrial pressure from 35 patients were plotted against simultaneous recordings of mean pulmonary capillary wedge pressure resulting in the correlation y = 0.88x + 3.3, r = 0.88, standard error of estimate = ±4 mm Hg (p < 0.001). Therefore, continuous-wave Doppler echocardiography and sphygmomanometry may be used in selected patients with congestive heart failure and mitral regurgitation for noninvasive estimation of left atrial pressure.
AB - A completely noninvasive method for estimating left atrial pressure in patients with congestive heart failure and mitral regurgitation has been devised with the use of continuous-wave Doppler echocardiography and brachial sphygmomanometry. Of 46 patients studied with mitral regurgitation, 35 (76%) had jets with distinct Doppler spectral envelopes recorded. The peak ventriculoatrial gradient was obtained by measuring peak mitral regurgitant velocity in systole and using the modified Bernoulli equation. This gradient was then subtracted from peak brachial systolic blood pressure, an estimate of left ventricular systolic pressure, to yield left atrial pressure (left atrial pressure = systolic blood pressure - mitral regurgitant pressure gradient). Noninvasive estimates of left atrial pressure from 35 patients were plotted against simultaneous recordings of mean pulmonary capillary wedge pressure resulting in the correlation y = 0.88x + 3.3, r = 0.88, standard error of estimate = ±4 mm Hg (p < 0.001). Therefore, continuous-wave Doppler echocardiography and sphygmomanometry may be used in selected patients with congestive heart failure and mitral regurgitation for noninvasive estimation of left atrial pressure.
UR - http://www.scopus.com/inward/record.url?scp=0026078388&partnerID=8YFLogxK
U2 - 10.1016/0002-8703(91)90199-R
DO - 10.1016/0002-8703(91)90199-R
M3 - Article
C2 - 2000753
AN - SCOPUS:0026078388
SN - 0002-8703
VL - 121
SP - 858
EP - 863
JO - American heart journal
JF - American heart journal
IS - 3 PART 1
ER -