Abstract
Dynamic solution: The title acids undergo dynamic kinetic resolution during an enantioselective esterification catalyzed by (S)-homobenzotetramisole ((S)-HBTM; see scheme). This method extends the scope of the carboxylic acid derivatives that are amenable to the nonenzymatic version of this transformation.
Original language | English |
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Pages (from-to) | 5553-5555 |
Number of pages | 3 |
Journal | Angewandte Chemie - International Edition |
Volume | 50 |
Issue number | 24 |
DOIs | |
State | Published - Jun 6 2011 |
Keywords
- acyl-transfer catalysis
- kinetic resolution
- organocatalysis
- racemization
- synthetic methods