Non-Invasive Measurements of Deep Tissue Hemodynamics in Human Skeletal Muscle

G. Yu, T. Durduran, G. Lech, C. Zhou, C. Britton, A. G. Yodh

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


A hybrid instrument combining near-infrared diffuse reflection spectroscopy and diffuse correlation spectroscopy (DCS) was used to simultaneously measure the concentration, oxygenation, and flow characteristics of blood cells in the same region of human skeletal muscles. The signals detected from different layers (skin, subcutaneous fat and muscle) were analyzed and the strongest response was found from muscle. The use of this hybrid instrument was demonstrated by characterizing the hemodynamic responses of nine healthy subjects and one patient with peripheral vascular disease (PVD) during arterial cuff occlusion of arm or leg and during plantar flexion exercise.

Original languageEnglish
Title of host publicationBiomedical Topical Meeting, BIOMED 2004
PublisherOptica Publishing Group (formerly OSA)
ISBN (Electronic)1557527695
StatePublished - 2004
EventBiomedical Topical Meeting, BIOMED 2004 - Miami Beach, United States
Duration: Apr 14 2004Apr 17 2004

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701


ConferenceBiomedical Topical Meeting, BIOMED 2004
Country/TerritoryUnited States
CityMiami Beach


Dive into the research topics of 'Non-Invasive Measurements of Deep Tissue Hemodynamics in Human Skeletal Muscle'. Together they form a unique fingerprint.

Cite this