TY - JOUR
T1 - Nomenclature of monocytes and dendritic cells in blood
AU - Ziegler-Heitbrock, Loems
AU - Ancuta, Petronela
AU - Crowe, Suzanne
AU - Dalod, Marc
AU - Grau, Veronika
AU - Hart, Derek N.
AU - Leenen, Pieter J.M.
AU - Liu, Yong Jun
AU - MacPherson, Gordon
AU - Randolph, Gwendalyn J.
AU - Scherberich, Juergen
AU - Schmitz, Juergen
AU - Shortman, Ken
AU - Sozzani, Silvano
AU - Strobl, Herbert
AU - Zembala, Marek
AU - Austyn, Jonathan M.
AU - Lutz, Manfred B.
PY - 2010/10/21
Y1 - 2010/10/21
N2 - Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community.
AB - Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community.
UR - http://www.scopus.com/inward/record.url?scp=77958185103&partnerID=8YFLogxK
U2 - 10.1182/blood-2010-02-258558
DO - 10.1182/blood-2010-02-258558
M3 - Review article
C2 - 20628149
AN - SCOPUS:77958185103
SN - 0006-4971
VL - 116
SP - e74-e80
JO - Blood
JF - Blood
IS - 16
ER -