TY - JOUR
T1 - No need to “sugar coat”
T2 - Removing glycocalyx on apoptotic blebs promotes phagocytosis
AU - Kelley, Shannon M.
AU - Ravichandran, Kodi S.
N1 - Publisher Copyright:
© 2024 Elsevier Inc.
PY - 2024/4/8
Y1 - 2024/4/8
N2 - The viscous glycocalyx of mammalian cells, composed of glucosaminoglycans, glycolipids, and glycoproteins, “sugar coat” the outer plasma membrane. In this issue of Developmental Cell, Le et al. (2024) show that the glycocalyx is removed from apoptotic blebs via disassembly of the cortical cytoskeleton, exposing the “eat-me” signals necessary for efferocytosis.
AB - The viscous glycocalyx of mammalian cells, composed of glucosaminoglycans, glycolipids, and glycoproteins, “sugar coat” the outer plasma membrane. In this issue of Developmental Cell, Le et al. (2024) show that the glycocalyx is removed from apoptotic blebs via disassembly of the cortical cytoskeleton, exposing the “eat-me” signals necessary for efferocytosis.
UR - http://www.scopus.com/inward/record.url?scp=85189520747&partnerID=8YFLogxK
U2 - 10.1016/j.devcel.2024.02.014
DO - 10.1016/j.devcel.2024.02.014
M3 - Comment/debate
C2 - 38593785
AN - SCOPUS:85189520747
SN - 1534-5807
VL - 59
SP - 827
EP - 829
JO - Developmental cell
JF - Developmental cell
IS - 7
ER -