No-Carrier-Added Radiohalogenation Methods with Heavy Halogens

H. H. Coenen, S. M. Moerlein, G. StCklin

Research output: Contribution to journalArticlepeer-review

120 Scopus citations

Abstract

Radiolabeling methods with the heavy halogens bromine, iodine and astatine are reviewed. The methods are evaluated on the basis of their underlying chemical principles and their usefulness for the no-carrier-added labeling of biologically-useful Compounds. Special emphasis is placed on the stability, specific activity, and quality control of radiohalogenation products using the short-lived, neutron-deficient nuclides 75,77Br, 123I,and 211At in view of their importance as radiopharmaceuticals.

Original languageEnglish
Pages (from-to)47-68
Number of pages22
JournalRadiochimica Acta
Volume34
Issue number1-2
DOIs
StatePublished - Oct 1983

Keywords

  • 123,125,131,I,211 At
  • 75,77 Br
  • Halogenated radiopharmaceu ticals
  • Radiohalogenation
  • n.c.a laheling

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