No-Carrier-Added Radiohalogenation Methods with Heavy Halogens

H. H. Coenen, S. M. Moerlein, G. StCklin

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Radiolabeling methods with the heavy halogens bromine, iodine and astatine are reviewed. The methods are evaluated on the basis of their underlying chemical principles and their usefulness for the no-carrier-added labeling of biologically-useful Compounds. Special emphasis is placed on the stability, specific activity, and quality control of radiohalogenation products using the short-lived, neutron-deficient nuclides 75,77Br, 123I,and 211At in view of their importance as radiopharmaceuticals.

Original languageEnglish
Pages (from-to)47-68
Number of pages22
JournalRadiochimica Acta
Issue number1-2
StatePublished - Oct 1983


  • 123,125,131,I,211 At
  • 75,77 Br
  • Halogenated radiopharmaceu ticals
  • Radiohalogenation
  • n.c.a laheling


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