NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the Ψ-RNA packaging signal. Implications for genome recognition

Keyphrases

• Human Immunodeficiency Virus Type 1 (HIV-1) 100%
• Protein Binding 100%
• Nucleocapsid Protein 100%
• Stem-loop 100%
• NMR Structure 100%
• Zinc Knuckle 100%
• RNA Packaging Signal 100%
• Major Groove 50%
• Minor Groove 50%
• Tight 25%
• Side Chain 25%
• Amino Acids 25%
• Structural Features 25%
• Hydrogen Bonds (H-bonds) 25%
• Electrostatic Interaction 25%
• Redundant Function 25%
• NMR Techniques 25%
• Tetraloop 25%
• Isotopically Labeled 25%
• Retrovirus 25%
• Guanosine 25%
• Phosphodiester 25%
• Specific Recognition 25%
• Multiple Sites 25%
• Virus Assembly 25%
• Intramolecular Interactions 25%
• 310-helix 25%
• Gag Polyprotein 25%
• Base Triple 25%
• Intermolecular Interactions 25%
• RNA Genome 25%
• Relative Orientation 25%
• Multinuclear NMR 25%
• N-terminal Helix 25%
• Packaging Signal 25%
• Hydrophobic Contacts 25%
• Packer Element 25%

Biochemistry, Genetics and Molecular Biology

• Human Immunodeficiency Virus 1 100%
• RNA 100%
• Virus Nucleocapsid 100%
• Stem-Loop 100%
• N-Terminus 29%
• C-Terminus 11%
• Amino Acids 5%
• Zinc 5%
• Static Electricity 5%
• Molecular Interaction 5%
• Virus Assembly 5%
• 310 Helix 5%
• Retrovirus 5%
• Tetraloop 5%
• Guanosine 5%