NMR spectroscopy of DNA/RNA hybrids

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RNA/DNA hybrids are formed in many biological processes. Earlier work on hybrid molecules had indicated that although their stability varied according to their sequence, all these duplexes were apparently A-form. Recent structural experiments have been directed toward defining how these hybrid A-form conformations differ from canonical RNA A-form duplexes.

Original languageEnglish
Pages (from-to)336-339
Number of pages4
JournalCurrent Opinion in Structural Biology
Issue number3
StatePublished - Jun 1993


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