Abstract

Natural killer (NK) cells are cytotoxic innate lymphocytes that can kill tumor cells. While a majority of the early studies on the role of NK cells in cancer focused on hematopoietic tumors, there has been a growing interest in the role of NK cells in solid tumors. NK cells are grouped with innate lymphoid cells (ILCs) that include ILC1, a closely related but distinct cell whose role in antitumor immunity is incompletely understood. In this review we focus primarily on the role of NK cells in solid tumors and review the limited data available on the role of ILC1s in cancer.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer
Pages41-55
Number of pages15
DOIs
StatePublished - 2022

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1365
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Cancer
  • ILC1s
  • NK cells
  • Solid tumor

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