Nifedipine in the prophylaxis of classic migraine: A crossover, double-masked, placebo-controlled study of headache frequency and side effects

J. C. McArthur; K. Marek; A. Pestronk; J. McArthur

doi:10.1212/wnl.39.2.284

Nifedipine in the prophylaxis of classic migraine: A crossover, double-masked, placebo-controlled study of headache frequency and side effects

J. C. McArthur
, K. Marek
, A. Pestronk
, J. McArthur

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Twenty-four patients with classic migraine attacks were treated with either nifedipine or placebo for up to 12 weeks. No significant differences were observed between the nifedipine (2.1 ± 0.2) and placebo (2.3 ± 0.2) treatment groups in the monthly frequency of headaches. However, the incidence of side effects was significantly greater (p < 0.001) in the nifedipine (54% of patients) than in the placebo (8% of patients) treatment groups.

Original language	English
Pages (from-to)	284-286
Number of pages	3
Journal	Neurology
Volume	39
Issue number	2
DOIs	https://doi.org/10.1212/wnl.39.2.284
State	Published - Feb 1989

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10.1212/wnl.39.2.284

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abstract = "Twenty-four patients with classic migraine attacks were treated with either nifedipine or placebo for up to 12 weeks. No significant differences were observed between the nifedipine (2.1 ± 0.2) and placebo (2.3 ± 0.2) treatment groups in the monthly frequency of headaches. However, the incidence of side effects was significantly greater (p < 0.001) in the nifedipine (54\% of patients) than in the placebo (8\% of patients) treatment groups.",

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AB - Twenty-four patients with classic migraine attacks were treated with either nifedipine or placebo for up to 12 weeks. No significant differences were observed between the nifedipine (2.1 ± 0.2) and placebo (2.3 ± 0.2) treatment groups in the monthly frequency of headaches. However, the incidence of side effects was significantly greater (p < 0.001) in the nifedipine (54% of patients) than in the placebo (8% of patients) treatment groups.

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Nifedipine in the prophylaxis of classic migraine: A crossover, double-masked, placebo-controlled study of headache frequency and side effects

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