Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development

Sadie VanHorn; Samantha A. Morris

doi:10.1016/j.devcel.2020.10.021

Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development

Sadie VanHorn, Samantha A. Morris

Research output: Contribution to journal › Review article › peer-review

57 Scopus citations

Abstract

VanHorn and Morris review the origins of fate mapping and lineage tracing approaches, focusing on how advances in single-cell genomics have fueled strategies to map lineage relationships. They explore how these technologies can be leveraged to synthesize high-resolution fate maps and their potential to provide insights into development.

Original language	English
Pages (from-to)	7-21
Number of pages	15
Journal	Developmental cell
Volume	56
Issue number	1
DOIs	https://doi.org/10.1016/j.devcel.2020.10.021
State	Published - Jan 11 2021

Keywords

fate mapping
lineage tracing
single-cell RNA sequencing
spatial transcriptomics

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10.1016/j.devcel.2020.10.021

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title = "Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development",

abstract = "VanHorn and Morris review the origins of fate mapping and lineage tracing approaches, focusing on how advances in single-cell genomics have fueled strategies to map lineage relationships. They explore how these technologies can be leveraged to synthesize high-resolution fate maps and their potential to provide insights into development.",

keywords = "fate mapping, lineage tracing, single-cell RNA sequencing, spatial transcriptomics",

author = "Sadie VanHorn and Morris, {Samantha A.}",

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KW - lineage tracing

KW - single-cell RNA sequencing

KW - spatial transcriptomics

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M3 - Review article

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Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development

Abstract

Keywords

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