Next-Generation Lineage Tracing and Fate Mapping to Interrogate Development

Sadie VanHorn, Samantha A. Morris

Research output: Contribution to journalReview articlepeer-review

Abstract

VanHorn and Morris review the origins of fate mapping and lineage tracing approaches, focusing on how advances in single-cell genomics have fueled strategies to map lineage relationships. They explore how these technologies can be leveraged to synthesize high-resolution fate maps and their potential to provide insights into development.

Original languageEnglish
Pages (from-to)7-21
Number of pages15
JournalDevelopmental cell
Volume56
Issue number1
DOIs
StatePublished - Jan 11 2021

Keywords

  • fate mapping
  • lineage tracing
  • single-cell RNA sequencing
  • spatial transcriptomics

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