Newer Surgical Options for Glaucoma

Behzad Amoozgar, Ingrid Chang, Jane Kuo, Ying Han

Research output: Contribution to journalReview articlepeer-review


Purpose of Review: Conventional filtering surgeries such as trabeculectomy and tube-shunt surgery have traditionally been considered the gold standard for management of glaucoma. However, they have a significant complication profile due to the invasive nature of the surgery, and have a relatively high risk of failure such as exuberant fibrotic responses leading to obstruction of the created outflow system. Due to these limitations of traditional incisional surgeries, new surgical techniques for management of glaucoma are of particular interest, especially in the setting of increasing prevalence of glaucoma with an aging population. These new procedures target either inflow or outflow system of the eye in order to manage the intraocular pressure (IOP). The recent innovative techniques share a common goal of effective intraocular pressure control while decreasing the complication profile and minimizing failure rate. This article reviews the primary challenges of developing a successful glaucoma surgery and the recent advancements in glaucoma laser and surgeries. Recent Findings: Recent surgical modalities have been designed to target eye inflow or outflow system. The advancements in their designs are based on detailed knowledge about eye fluidic system. These new developments have been associated with higher success rate and lower complications. More detailed investigations are currently being conducted regarding the long-term safety and repeatability of these interventions. Summary: Advanced surgical modalities have shown promising results in modulating IOP, minimizing the complications, lessening the exaggerated inflammatory-fibrotic response, and reducing the number of post-surgical medications.

Original languageEnglish
Pages (from-to)58-66
Number of pages9
JournalCurrent Ophthalmology Reports
Issue number1
StatePublished - Mar 1 2017


  • Intraocular pressure
  • Micropulse laser
  • Minimally invasive glaucoma surgery
  • Trabecular meshwork
  • Trabeculotomy


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