Drosophila is an ideal system for identifying genes that control central nervous system (CNS) development. Particularly useful tools include molecular markers for subsets of neural precursors (neuroblasts) and the simple expression pattern of the even-skipped (eve) gene in a subset of neurons. Here we provide additional molecular markers for identified neuroblasts, including several with near single cell specificity. In addition, we use these new markers to trace the development of several eve+ neurons. Our results shows that the eve+ aCC/pCC neurons develop from a different neuroblast than previously thought, and have led us to assign new names for several neuroblasts. These results are supported by DiI cell lineage analysis of neuroblasts identified in vivo.

Original languageEnglish
Pages (from-to)393-402
Number of pages10
JournalMechanisms of Development
Issue number3
StatePublished - Nov 1995


  • Central nervous system
  • Drosophila
  • Even-skipped
  • Ganglion mother cell
  • Gooseberry
  • Neural precursor
  • Neuroblast


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