New insights into the pathophysiology of Parkinson's disease: the challenge of positron emission tomography

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Positron emission tomography (PET) permits the quantitative in-vivo measurement of regional brain hemodynamics, metabolism, receptor pharmacology and neurotransmitter metabolism in human subjects. As such, it promised to reveal unique insights into the pathophysiology of brain disorders such as Parkinson's disease. However, preliminary studies of Parkinson's disease have frequently presented conflicting results that seem to obscure, rather than clarify, underlying disease processes. This apparent failure reflects early methodological difficulties; recent technical advances have led to the disclosure of exciting new avenues of investigation.

Original languageEnglish
Pages (from-to)203-208
Number of pages6
JournalTrends in Neurosciences
Volume11
Issue number5
DOIs
StatePublished - 1988

Fingerprint

Dive into the research topics of 'New insights into the pathophysiology of Parkinson's disease: the challenge of positron emission tomography'. Together they form a unique fingerprint.

Cite this