New Concepts in Steroid Glaucoma

A. M. Levin, E. G. Sieck

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of Review: In this article, we discuss the pathophysiology underlying intraocular pressure elevation associated with corticosteroid use as well as targeted therapies for treatment. Recent Findings: Several signaling pathways at the level of the trabecular meshwork are altered by steroid exposure. A pre-existing diagnosis of glaucoma is the best-established risk factor for development of steroid-associated ocular hypertension. Topical, local, and systemic steroids have all been associated with ocular hypertension. Summary: Current management is directed at steroid-sparing alternatives to treatment, steroid cessation, IOP-lowering medications, and interventional lasers and surgery.

Original languageEnglish
Pages (from-to)78-82
Number of pages5
JournalCurrent Ophthalmology Reports
Volume11
Issue number4
DOIs
StatePublished - Dec 2023

Keywords

  • Corticosteroids
  • Intraocular pressure
  • Secondary open-angle glaucoma
  • Steroid-induced glaucoma
  • Trabecular meshwork
  • Uveitis

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