Nevoid hyperkeratosis of the areola misinterpreted as mycosis fungoides

Ilana S. Rosman, Donna M. Hepper, Anne C. Lind, Milan J. Anadkat

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9 Scopus citations

Abstract

Nevoid hyperkeratosis of the nipple and areola is a benign condition with fewer than 70 cases reported in the literature. We report a case of unilateral nevoid hyperkeratosis of the areola with intraepidermal lymphocytes that resembled Pautrier's microabscesses on histological examination. This is the third report of mycosis fungoides-like changes in nevoid hyperkeratosis of the nipple and areola. In addition, this is the first case to present immunohistochemical and T-cell gene rearrangement studies of the intraepidermal lymphocytes. This case highlights a potential histopathological pitfall in the diagnosis of nevoid hyperkeratosis of the nipple and areola. Rosman IS, Hepper DM, Lind AC, Anadkat MJ. Nevoid hyperkeratosis of the areola misinterpreted as mycosis fungoides.

Original languageEnglish
Pages (from-to)545-548
Number of pages4
JournalJournal of cutaneous pathology
Volume39
Issue number5
DOIs
StatePublished - May 2012

Keywords

  • mycosis fungoides
  • nevoid hyperkeratosis
  • pitfall
  • simulant

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