Neuropathy: Metabolically-Induced

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Metabolic peripheral neuropathies include those that accompany diabetes and vitamin deficiencies and those in response to systemic disorders (e.g., uremia, hypothyroidism, acromegaly). Most of this metabolically focused segment deals with diabetic neuropathies, by far the most common neuropathies in Europe and North America. Diabetic neuropathy, which may predispose to limb amputation, is expected to burgeon in number as the result of the looming global obesity-driven epidemic of type 2 diabetes. This segment focuses on the multiple clinical and pathological patterns of diabetic neuropathy, which may involve sensory (some painful), motor, and autonomic functions. Other segments focus on peripheral nerve participation in systemic conditions which include kidney and hepatic failure, vitamin deficiencies, response to hypothyroidism, and alcoholism.

Original languageEnglish
Title of host publicationEncyclopedia of Neuroscience
PublisherElsevier Ltd
Number of pages9
ISBN (Print)9780080450469
StatePublished - 2009


  • Acromegaly
  • Autonomic nervous system
  • Diabetes
  • Ganglia
  • Hepatic
  • Neuropathy
  • Pathology
  • Sensory
  • Sympathetic
  • Thyroid
  • Uremia
  • Vitamin deficiency


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