TY - JOUR
T1 - Neuronal evidence for good-based economic decisions under variable action costs
AU - Cai, Xinying
AU - Padoa-Schioppa, Camillo
N1 - Funding Information:
We thank Heide Schoknecht for help with animal training and Katherine Conen for insightful discussions. We also thank Sebastien Ballesta, Katherine Conen, Ahmad Jez-zini, Masaru Kuwabara, Alessandro Livi, Weikang Shi, and Jue Xie for comments on the manuscript. This research was supported by the National Institutes of Health (grant number R01-DA032758 to CPS), the National Natural Science Foundation of China (grants 31571102 and 91632106 to XC), the Program of Introducing Talents of Discipline to Universities (Ministry of Education of China, Base B16018), the Joint Research Institute Seed Grants for Research Collaboration from the NYU-ECNU Institute of Brain and Cognitive Science at NYU Shanghai (to X.C.) and the Science and Technology Commission of Shanghai Municipality (grants 15JC1400104 and 16JC1400101 to XC).
Publisher Copyright:
© 2019, The Author(s).
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Previous work showed that economic decisions can be made independently of spatial contingencies. However, when goods available for choice bear different action costs, the decision necessarily reflects aspects of the action. One possibility is that “stimulus values” are combined with the corresponding action costs in a motor representation, and decisions are then made in actions space. Alternatively, action costs could be integrated with other determinants of value in a non-spatial representation. If so, decisions under variable action costs could take place in goods space. Here, we recorded from orbitofrontal cortex while monkeys chose between different juices offered in variable amounts. We manipulated action costs by varying the saccade amplitude, and we dissociated in time and space offer presentation from action planning. Neurons encoding the binary choice outcome did so well before the presentation of saccade targets, indicating that decisions were made in goods space.
AB - Previous work showed that economic decisions can be made independently of spatial contingencies. However, when goods available for choice bear different action costs, the decision necessarily reflects aspects of the action. One possibility is that “stimulus values” are combined with the corresponding action costs in a motor representation, and decisions are then made in actions space. Alternatively, action costs could be integrated with other determinants of value in a non-spatial representation. If so, decisions under variable action costs could take place in goods space. Here, we recorded from orbitofrontal cortex while monkeys chose between different juices offered in variable amounts. We manipulated action costs by varying the saccade amplitude, and we dissociated in time and space offer presentation from action planning. Neurons encoding the binary choice outcome did so well before the presentation of saccade targets, indicating that decisions were made in goods space.
UR - http://www.scopus.com/inward/record.url?scp=85060381981&partnerID=8YFLogxK
U2 - 10.1038/s41467-018-08209-3
DO - 10.1038/s41467-018-08209-3
M3 - Article
C2 - 30674879
AN - SCOPUS:85060381981
SN - 2041-1723
VL - 10
JO - Nature communications
JF - Nature communications
IS - 1
M1 - 393
ER -