Neurological complications in patients with SARS-CoV-2 infection: A systematic review

Renato Puppi Munhoz, José Luiz Pedroso, Fábio Augusto Nascimento, Sergio Monteiro De Almeida, Orlando Graziani Povoas Barsottini, Francisco Eduardo C. Cardoso, Hélio A.Ghizoni Teive

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

Background: As the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations. Objective: To review the literature on neurological complications of SARS-CoV-2 infection. Methods: Literature search performed following systematic reviews guidelines, using specific keywords based on the COVID-19 neurological complications described up to May 10th, 2020. Results: A total of 43 articles were selected, including data ranging from common, non-specific symptoms, such as hyposmia and myalgia, to more complex and life-Threatening conditions, such as cerebrovascular diseases, encephalopathies, and Guillain-Barré syndrome. Conclusion: Recognition of neurological manifestations of SARS-CoV-2 should be emphasized despite the obvious challenges faced by clinicians caring for critical patients who are often sedated and presenting other concurrent systemic complications.

Original languageEnglish
Pages (from-to)290-300
Number of pages11
JournalArquivos de Neuro-Psiquiatria
Volume78
Issue number5
DOIs
StatePublished - May 2020

Keywords

  • Coronavirus Infections
  • Covid-19
  • Encephalitis
  • Guillain-barré syndrome
  • Neurology
  • Stroke

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