Neurologic and cognitive outcomes in sickle cell disease from infancy through adolescence

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2 Scopus citations

Abstract

Children with sickle cell disease (SCD) are at risk for neurologic and cognitive complications beginning in early childhood. Current treatment for SCD focuses on primary prevention of complications, such as hydroxyurea for prevention of pain and acute chest syndrome, and chronic transfusion therapy for children who are at high risk for strokes. In this article, the prevalence, pathophysiology, and available interventions to prevent and treat neurologic and cognitive complications of SCD will be reviewed.

Original languageEnglish
Pages (from-to)e531-e539
JournalNeoReviews
Volume22
Issue number8
DOIs
StatePublished - Aug 2021

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