Essential tremor is one of the most common neurologic movement disorders with a prevalence between 0.3% and 4% in the United States (1) and may affect the limbs, head, neck, voice, or various combinations. About half of the patients have an autosomal dominant pattern of inheritance (2,3) but only two different gene loci have been linked to essential tremor in different pedigrees (4,5). The underlying pathophysiology remains elusive with no clear findings on patho- logic examinations of brains (6,7). Neuroimaging, however, has provided several clues to the pathophysiology of essential tremor and mechanisms of action of herapeutic interventions.
|Title of host publication||Handbook of Essential Tremor and Other Tremor Disorders|
|Number of pages||12|
|State||Published - Jan 1 2005|