TY - JOUR
T1 - Neurogenesis in the insect central nervous system
AU - Doe, Chris Q.
AU - Skeath, James B.
N1 - Funding Information:
We thank Bill Chia for comments on an early version of this manuscript. Work in our lab is supported by a Damon Runyon-Walter Winchell Cancer Research Postdoctoral Fellowship (JB Skeath) and the National Institutes of Health, Human Frontier Science Program, and Howard Hughes Medical Institute (CQ Doe). CQ Doe is an Assistant Investigator of the Howard Hughes Medical Institute.
PY - 1996/2
Y1 - 1996/2
N2 - Recent advances provide an increasingly sophisticated understanding of Drosophila CNS development. First, genes have been identified that specify unique neuroblast cell fates. Second, neuroblasts have been found to use a novel mechanism for asymmetric localization of proteins into one daughter cell at mitosis. Third, a gene controlling the choice between glial/neuronal determination has been discovered. And finally, new cell-lineage methods are being used to determine the entire lineage of identified neuroblasts, including axon projections and synaptic contacts.
AB - Recent advances provide an increasingly sophisticated understanding of Drosophila CNS development. First, genes have been identified that specify unique neuroblast cell fates. Second, neuroblasts have been found to use a novel mechanism for asymmetric localization of proteins into one daughter cell at mitosis. Third, a gene controlling the choice between glial/neuronal determination has been discovered. And finally, new cell-lineage methods are being used to determine the entire lineage of identified neuroblasts, including axon projections and synaptic contacts.
UR - http://www.scopus.com/inward/record.url?scp=0029930495&partnerID=8YFLogxK
U2 - 10.1016/S0959-4388(96)80004-3
DO - 10.1016/S0959-4388(96)80004-3
M3 - Article
C2 - 8794042
AN - SCOPUS:0029930495
SN - 0959-4388
VL - 6
SP - 18
EP - 24
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
IS - 1
ER -