98 Scopus citations


Recent advances provide an increasingly sophisticated understanding of Drosophila CNS development. First, genes have been identified that specify unique neuroblast cell fates. Second, neuroblasts have been found to use a novel mechanism for asymmetric localization of proteins into one daughter cell at mitosis. Third, a gene controlling the choice between glial/neuronal determination has been discovered. And finally, new cell-lineage methods are being used to determine the entire lineage of identified neuroblasts, including axon projections and synaptic contacts.

Original languageEnglish
Pages (from-to)18-24
Number of pages7
JournalCurrent Opinion in Neurobiology
Issue number1
StatePublished - Feb 1996


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