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Neuroexcitatory actions of Tamiflu and its carboxylate metabolite
Yukitoshi Izumi
, Kazuhiro Tokuda
, Kazuko A. O'Dell
,
Charles F. Zorumski
, Toshio Narahashi
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
DBBS - Neurosciences
DBBS - Biochemistry, Biophysics, and Structural Biology
Intellectual and Developmental Disabilities Research Center (IDDRC)
Hope Center for Neurological Disorders
Division of Basic Science Research
Research output
:
Contribution to journal
›
Article
›
peer-review
83
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Scopus citations
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Keyphrases
Carboxylate
100%
Oseltamivir
100%
Tamiflu
100%
Central Nervous System
22%
Ethanol Injection
22%
Oseltamivir Carboxylate
22%
Adverse Effects
11%
Japan
11%
Juvenile Rats
11%
Hippocampal Slice
11%
Ethanol
11%
Avian Influenza
11%
H5N1
11%
Reflex
11%
Abnormal Behavior
11%
GABAergic
11%
Hypothermia
11%
Disinhibition
11%
Rat Hippocampal Slices
11%
Paired-pulse Facilitation
11%
CA1 Region
11%
Systemic Injection
11%
Active Metabolite
11%
Behavior Change
11%
Neuronal Firing
11%
Excitatory Postsynaptic Potential
11%
Safe Administration
11%
Neuropsychiatric Adverse Events
11%
Seasonal Influenza
11%
Population Spike
11%
Lightning
11%
Abnormal Death
11%
Pharmacology, Toxicology and Pharmaceutical Science
Carboxylate
100%
Oseltamivir
100%
4 Acetamido 5 Amino 3 (1 Ethylpropoxy) 1 Cyclohexene 1 Carboxylic Acid
15%
Hypothermia
7%
Active Metabolite
7%
Seasonal Influenza
7%
Avian Influenza
7%
Influenza A Virus (H5N1)
7%
Abnormal Behavior
7%
Neuroscience
Carboxylic Acid
100%
Oseltamivir
100%
Central Nervous System
13%
Adverse Effect
6%
Behavior (Neuroscience)
6%
Disinhibition
6%
Excitatory Postsynaptic Potential
6%
Hypothermia
6%
Abnormal Behavior
6%