Neuroendocrine Tumors of the Lung

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Abstract

Pulmonary neuroendocrine tumors (NETs) are relatively rare; however, their incidence is steadily increasing. They now comprise 1% to 2% of all lung cancers. Lung NETs are classified based on the World Health Organization classification into low-, intermediate-, and high-grade tumors. Most patients present with nonspecific symptoms that can result in delayed diagnosis. Bronchoscopy and biopsy are essential to diagnose and classify pulmonary NETs. Surgery is the mainstay of therapy and R0 resection is key. Lung preservation surgery, whenever possible, is preferred. There is little role of systemic therapy in NETs. Survival after R0 resection is reasonably good especially in low-grade tumors.

Original languageEnglish
Pages (from-to)469-476
Number of pages8
JournalThoracic surgery clinics
Volume31
Issue number4
DOIs
StatePublished - Nov 1 2021

Keywords

  • Bronchoscopy
  • Carcinoid
  • Neuroendocrine tumors
  • Sleeve lobectomy

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