Neural tuners of lung immunity

Tiago H. Zaninelli; Felipe A. Pinho-Ribeiro

doi:10.1016/j.immuni.2025.07.015

Neural tuners of lung immunity

Tiago H. Zaninelli
, Felipe A. Pinho-Ribeiro

Research output: Contribution to journal › Comment/debate

Abstract

Pulmonary immunity must strike a precise balance between protecting the delicate mucosal tissue from environmental threats and preserving its vital gas-exchange function. In this issue of Immunity, Li et al. and Hiroki et al. illuminate how the nervous system mediates this balance by wiring distinct sympathetic and sensory circuits to macrophage subsets, offering new therapeutic strategies for pneumonia and pulmonary fibrosis.

Original language	English
Pages (from-to)	1887-1889
Number of pages	3
Journal	Immunity
Volume	58
Issue number	8
DOIs	https://doi.org/10.1016/j.immuni.2025.07.015
State	Published - Aug 12 2025

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title = "Neural tuners of lung immunity",

abstract = "Pulmonary immunity must strike a precise balance between protecting the delicate mucosal tissue from environmental threats and preserving its vital gas-exchange function. In this issue of Immunity, Li et al. and Hiroki et al. illuminate how the nervous system mediates this balance by wiring distinct sympathetic and sensory circuits to macrophage subsets, offering new therapeutic strategies for pneumonia and pulmonary fibrosis.",

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T1 - Neural tuners of lung immunity

AU - Zaninelli, Tiago H.

AU - Pinho-Ribeiro, Felipe A.

PY - 2025/8/12

Y1 - 2025/8/12

N2 - Pulmonary immunity must strike a precise balance between protecting the delicate mucosal tissue from environmental threats and preserving its vital gas-exchange function. In this issue of Immunity, Li et al. and Hiroki et al. illuminate how the nervous system mediates this balance by wiring distinct sympathetic and sensory circuits to macrophage subsets, offering new therapeutic strategies for pneumonia and pulmonary fibrosis.

AB - Pulmonary immunity must strike a precise balance between protecting the delicate mucosal tissue from environmental threats and preserving its vital gas-exchange function. In this issue of Immunity, Li et al. and Hiroki et al. illuminate how the nervous system mediates this balance by wiring distinct sympathetic and sensory circuits to macrophage subsets, offering new therapeutic strategies for pneumonia and pulmonary fibrosis.

UR - https://www.scopus.com/pages/publications/105012452042

U2 - 10.1016/j.immuni.2025.07.015

DO - 10.1016/j.immuni.2025.07.015

M3 - Comment/debate

C2 - 40803314

AN - SCOPUS:105012452042

SN - 1074-7613

VL - 58

SP - 1887

EP - 1889

JO - Immunity

JF - Immunity

IS - 8

ER -

Neural tuners of lung immunity

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