Nephrotic range proteinuria associated with focal segmental glomerulosclerosis reversed with pioglitazone therapy in a patient with Dunnigan type lipodystrophy

Anjul Sharma, Raymond E. Bourey, John C. Edwards, David S. Brink, Stewart G. Albert

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Familial partial lipodystrophy (FPLD) is a rare disorder associated with severe insulin resistance, hypertriglyceridemia, low serum HDL cholesterol and proteinuric renal disease. Although proteinuric renal disease is not common among in patients with partial lipodystrophy, we report a patient with Dunnigan type FPLD complicated by nephrotic syndrome which resolved following treatment with the PPARγ agonist pioglitazone, CPAP, diet, and exercise.

Original languageEnglish
Article number108620
JournalDiabetes Research and Clinical Practice
Volume172
DOIs
StatePublished - Feb 2021

Keywords

  • Diabetes mellitus
  • Diabetic proteinuria
  • Focal segmental glomerulosclerosis
  • Lipodystrophy syndrome
  • Pioglitazone

Fingerprint

Dive into the research topics of 'Nephrotic range proteinuria associated with focal segmental glomerulosclerosis reversed with pioglitazone therapy in a patient with Dunnigan type lipodystrophy'. Together they form a unique fingerprint.

Cite this