Nephron-sparing surgery in children with primary renal tumor: Indications and results

Denis Andrew Cozzi; Augusto Zani

doi:10.1053/j.sempedsurg.2005.11.002

Nephron-sparing surgery in children with primary renal tumor: Indications and results

Denis Andrew Cozzi
, Augusto Zani

Division of Pediatric Surgery

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including children with genetic syndromes, children younger than 1 year of age, and children with hyperplastic nephroblastomatosis. The use of NSS in selected children with "low-risk" or stage I "intermediate-risk" WT and a normal contralateral kidney is still controversial. Available data suggest that, in children with WT, NSS does not impair the outcome and has a renal function advantage over nephrectomy.

Original language	English
Pages (from-to)	3-9
Number of pages	7
Journal	Seminars in pediatric surgery
Volume	15
Issue number	1
DOIs	https://doi.org/10.1053/j.sempedsurg.2005.11.002
State	Published - Feb 2006

Keywords

Congenital mesoblastic nephroma
Cystic nephroma
Cystic partially differentiated nephroblastoma
Enucleation
Nephroblastoma
Nephroblastomatosis
Oncocitoma
Partial nephrectomy
Wilms' tumor

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10.1053/j.sempedsurg.2005.11.002

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abstract = "Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including children with genetic syndromes, children younger than 1 year of age, and children with hyperplastic nephroblastomatosis. The use of NSS in selected children with {"}low-risk{"} or stage I {"}intermediate-risk{"} WT and a normal contralateral kidney is still controversial. Available data suggest that, in children with WT, NSS does not impair the outcome and has a renal function advantage over nephrectomy.",

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T1 - Nephron-sparing surgery in children with primary renal tumor

T2 - Indications and results

AU - Cozzi, Denis Andrew

AU - Zani, Augusto

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N2 - Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including children with genetic syndromes, children younger than 1 year of age, and children with hyperplastic nephroblastomatosis. The use of NSS in selected children with "low-risk" or stage I "intermediate-risk" WT and a normal contralateral kidney is still controversial. Available data suggest that, in children with WT, NSS does not impair the outcome and has a renal function advantage over nephrectomy.

AB - Nephron-sparing surgery (NSS) is the treatment of choice for children with bilateral Wilms' tumor (WT), or with WT on a single kidney, or with WT and a disease of the contralateral kidney, or with benign kidney tumor. NSS is a reasonable alternative to nephrectomy in children at risk of metachronous WT, including children with genetic syndromes, children younger than 1 year of age, and children with hyperplastic nephroblastomatosis. The use of NSS in selected children with "low-risk" or stage I "intermediate-risk" WT and a normal contralateral kidney is still controversial. Available data suggest that, in children with WT, NSS does not impair the outcome and has a renal function advantage over nephrectomy.

KW - Congenital mesoblastic nephroma

KW - Cystic nephroma

KW - Cystic partially differentiated nephroblastoma

KW - Enucleation

KW - Nephroblastoma

KW - Nephroblastomatosis

KW - Oncocitoma

KW - Partial nephrectomy

KW - Wilms' tumor

UR - https://www.scopus.com/pages/publications/31744437758

U2 - 10.1053/j.sempedsurg.2005.11.002

DO - 10.1053/j.sempedsurg.2005.11.002

M3 - Article

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AN - SCOPUS:31744437758

SN - 1055-8586

VL - 15

SP - 3

EP - 9

JO - Seminars in pediatric surgery

JF - Seminars in pediatric surgery

IS - 1

ER -

Nephron-sparing surgery in children with primary renal tumor: Indications and results

Abstract

Keywords

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