Nephrogenic fibrosing dermopathy in pediatric patients

Sima M. Jain, Stanton Wesson, Ashraf Hassanein, Erica Canova, Miranda Hoy, Robert S. Fennell, Vikas R. Dharnidharka

Research output: Contribution to journalReview articlepeer-review

68 Scopus citations


Nephrogenic fibrosing dermopathy (NFD) is a rare and recently recognized sclerosing skin disorder of unknown etiology. Reported cases have occurred in patients with chronic renal failure, with or without renal replacement therapy. All previous cases have been reported in older adult patients. We describe two pediatric patients who recently developed this condition and review the existing literature for NFD. Our patients included an 8-year-old boy on peritoneal dialysis with no prior renal transplant and a 19-year-old boy on hemodialysis with a history of previous failed renal transplants. We speculate that the recent emergence of this condition and occurrence in patients with chronic renal failure suggest an association with some newer pharmacological agent that has recently come into wide use. Since both our patients also had previously experienced large vessel thrombosis, hypercoagulable states may also be implicated.

Original languageEnglish
Pages (from-to)467-470
Number of pages4
JournalPediatric Nephrology
Issue number4
StatePublished - Apr 1 2004


  • Nephrogenic fibrosing dermopathy
  • Renal failure


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