TY - JOUR
T1 - Neonatal outcomes in twin pregnancies complicated by gestational diabetes compared with non-diabetic twins
AU - Foeller, M. E.
AU - Zhao, S.
AU - Szabo, A.
AU - Cruz, M. O.
N1 - Publisher Copyright:
© 2015 Nature America, Inc. All rights reserved.
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Objective: To compare neonatal outcomes of twin pregnancies with gestational diabetes (GDM) and preexisting diabetes with non-diabetic twin pregnancies. Study Design: US birth data from 2006 to 2009 was used to compare twin pregnancies of 16 562 GDM and 2137 preexisting diabetic with 258 857 non-diabetic twin gestations. Adjusted odds ratios (aORs) were calculated to assess effects of GDM and preexisting diabetes on neonatal outcomes. Result: Twin pregnancies with GDM vs non-diabetic twin pregnancies demonstrated decreased 5-min Apgar scores <4 (aOR 0.8, 95% confidence interval (CI) 0.68-0.94), fewer births before 32 weeks gestation (aOR 0.72, 95% CI 0.68-0.76), decreased birth weight less than the tenth percentile (aOR 0.84, 95% CI 0.81-0.89) and fifth percentile (aOR 0.85, 95% CI 0.81-0.89) and a trend toward lower rates of neonatal death (aOR 0.84, 95% CI 0.68-1.02). Conclusion: Certain adverse outcomes in pregnancies with GDM may be attenuated in twin gestations; however, further investigation is warranted.
AB - Objective: To compare neonatal outcomes of twin pregnancies with gestational diabetes (GDM) and preexisting diabetes with non-diabetic twin pregnancies. Study Design: US birth data from 2006 to 2009 was used to compare twin pregnancies of 16 562 GDM and 2137 preexisting diabetic with 258 857 non-diabetic twin gestations. Adjusted odds ratios (aORs) were calculated to assess effects of GDM and preexisting diabetes on neonatal outcomes. Result: Twin pregnancies with GDM vs non-diabetic twin pregnancies demonstrated decreased 5-min Apgar scores <4 (aOR 0.8, 95% confidence interval (CI) 0.68-0.94), fewer births before 32 weeks gestation (aOR 0.72, 95% CI 0.68-0.76), decreased birth weight less than the tenth percentile (aOR 0.84, 95% CI 0.81-0.89) and fifth percentile (aOR 0.85, 95% CI 0.81-0.89) and a trend toward lower rates of neonatal death (aOR 0.84, 95% CI 0.68-1.02). Conclusion: Certain adverse outcomes in pregnancies with GDM may be attenuated in twin gestations; however, further investigation is warranted.
UR - http://www.scopus.com/inward/record.url?scp=84948082121&partnerID=8YFLogxK
U2 - 10.1038/jp.2015.133
DO - 10.1038/jp.2015.133
M3 - Article
C2 - 26513454
AN - SCOPUS:84948082121
SN - 0743-8346
VL - 35
SP - 1043
EP - 1047
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 12
ER -