Neocortical neuron morphology in Afrotheria: Comparing the rock hyrax with the African elephant

Serena Bianchi, Amy L. Bauernfeind, Kanika Gupta, Cheryl D. Stimpson, Muhammad A. Spocter, Christopher J. Bonar, Paul R. Manger, Patrick R. Hof, Bob Jacobs, Chet C. Sherwood

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The mammalian neocortex contains a great variety of neuronal types. In particular, recent studies have shown substantial morphological diversity among spiny projecting neurons in species that diverged close to the base of the mammalian radiation (e.g., monotremes, afrotherians, and xenarthrans). Here, we used a Golgi technique to examine different neuronal morphologies in an afrotherian species, the rock hyrax (Procavia capensis), and provide a comparison with the related African elephant (Loxodonta africana). Results showed that spiny neurons in the rock hyrax neocortex exhibit less morphological variation than in elephants, displaying a higher frequency of relatively "typical" pyramidal neurons. A quantitative comparison of rock hyrax pyramidal neuron morphology between frontal and visual areas, moreover, revealed greater spine density of neurons in frontal cortex, but no differences in other morphological aspects. Regional variations in pyramidal structure have also been observed in the African elephant, as well as a number of primate species.

Original languageEnglish
Pages (from-to)37-46
Number of pages10
JournalAnnals of the New York Academy of Sciences
Volume1225
Issue number1
DOIs
StatePublished - Apr 2011

Keywords

  • Afrotheria
  • Dendrite
  • Elephant
  • Evolution
  • Golgi
  • Rock hyrax

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    Bianchi, S., Bauernfeind, A. L., Gupta, K., Stimpson, C. D., Spocter, M. A., Bonar, C. J., Manger, P. R., Hof, P. R., Jacobs, B., & Sherwood, C. C. (2011). Neocortical neuron morphology in Afrotheria: Comparing the rock hyrax with the African elephant. Annals of the New York Academy of Sciences, 1225(1), 37-46. https://doi.org/10.1111/j.1749-6632.2011.05991.x