TY - JOUR
T1 - Nedraugiška ugnis
T2 - kaip tabako pramonė griauna mūsų vaikų ateitį
AU - Bush, Andrew
AU - Ferkol, Thomas
AU - Valiulis, Algirdas
AU - Mazur, Artur
AU - Chkhaidze, Ivane
AU - Maglakelidze, Tamaz
AU - Sargsyan, Sergey
AU - Boyajyan, Gevorg
AU - Cirstea, Olga
AU - Doan, Svitlana
AU - Katilov, Oleksandr
AU - Pokhylko, Valeriy
AU - Dubey, Leonid
AU - Poluziorovienė, Edita
AU - Prokopčiuk, Nina
AU - Taminskienė, Vaida
AU - Valiulis, Arūnas
N1 - Publisher Copyright:
© 2021 Andrew Bush, Thomas Ferkol, Algirdas Valiulis, Artur Mazur, Ivane Chkhaidze, Tamaz Maglakelidze, Sergey Sargsyan, Gevorg Boyajyan, Olga Cirstea, Svitlana Doan, Oleksandr Katilov, Valeriy Pokhylko, Leonid Dubey, Edita Poluziorovienė, Nina Prokopčiuk, Vaida Taminskienė, Arūnas Valiulis.
PY - 2021
Y1 - 2021
N2 - Tobacco has long been known to be one of the greatest causes of morbidity and mortality in the adults, but the effects on the foetus and young children, which are lifelong, have been less well appreciated. Developing from this are electronic nicotine delivery systems or vapes, promulgated as being less harmful than tobacco. Nicotine itself is toxic to the foetus, with permanent effects on lung structure and function. Most vapes contain nicotine, but they also contain many other compounds which are inhaled and for which there are no toxicity studies. They also contain known toxic substances, whose use is banned by European Union legislation. Accelerating numbers of young people are vaping, and this does not reflect an exchange of vapes for cigarettes. The acute toxicity of e-cigarettes is greater than that of tobacco, and includes acute lung injury, pulmonary haemorrhage and eosinophilic and lipoid pneumonia. Given the worse acute toxicity, it should be impossible to be complacent about medium and long term effects of vaping. Laboratory studies have demonstrated changes in lung proteomics and the innate immune system with vaping, some but not all of which overlap with tobacco. It would be wrong to consider vapes as a weaker form of tobacco, they have their own toxicity. Children and young people are being targeted by the vaping industry (which is largely the same as the tobacco industry), including on-line, and unless an efficient legislative program is put in place, a whole new generation of nicotine addicts will result.
AB - Tobacco has long been known to be one of the greatest causes of morbidity and mortality in the adults, but the effects on the foetus and young children, which are lifelong, have been less well appreciated. Developing from this are electronic nicotine delivery systems or vapes, promulgated as being less harmful than tobacco. Nicotine itself is toxic to the foetus, with permanent effects on lung structure and function. Most vapes contain nicotine, but they also contain many other compounds which are inhaled and for which there are no toxicity studies. They also contain known toxic substances, whose use is banned by European Union legislation. Accelerating numbers of young people are vaping, and this does not reflect an exchange of vapes for cigarettes. The acute toxicity of e-cigarettes is greater than that of tobacco, and includes acute lung injury, pulmonary haemorrhage and eosinophilic and lipoid pneumonia. Given the worse acute toxicity, it should be impossible to be complacent about medium and long term effects of vaping. Laboratory studies have demonstrated changes in lung proteomics and the innate immune system with vaping, some but not all of which overlap with tobacco. It would be wrong to consider vapes as a weaker form of tobacco, they have their own toxicity. Children and young people are being targeted by the vaping industry (which is largely the same as the tobacco industry), including on-line, and unless an efficient legislative program is put in place, a whole new generation of nicotine addicts will result.
KW - Acute lung injury
KW - Alveolar haemorrhage
KW - Children
KW - E-cigarettes
KW - EVALI
KW - Eosinophilic pneumonia
KW - Innate immune system
KW - Lipoid pneumonia
KW - Nicotine
KW - Vaping
UR - http://www.scopus.com/inward/record.url?scp=85111393769&partnerID=8YFLogxK
U2 - 10.15388/Amed.2020.28.1.6
DO - 10.15388/Amed.2020.28.1.6
M3 - Article
C2 - 34393624
AN - SCOPUS:85111393769
SN - 1392-0138
VL - 28
SP - 6
EP - 18
JO - Acta Medica Lituanica
JF - Acta Medica Lituanica
IS - 1
ER -