Nedd4 Branches Out

Aaron DiAntonio

doi:10.1016/j.neuron.2010.01.028

Nedd4 Branches Out

Aaron DiAntonio

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

The branching of dendrites and axons is a key determinant of neural circuit formation. In this issue of Neuron, Kawabe et al. demonstrate that the ubiquitin ligase Nedd4 promotes the branching of developing dendrites by targeting the small G protein Rap2. In a complementary study, Drinjakovic et al. show that Nedd4 promotes the branching of developing axons by ubiquitinating a different target, the phosphatase PTEN.

Original language	English
Pages (from-to)	293-294
Number of pages	2
Journal	Neuron
Volume	65
Issue number	3
DOIs	https://doi.org/10.1016/j.neuron.2010.01.028
State	Published - Feb 11 2010

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10.1016/j.neuron.2010.01.028

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title = "Nedd4 Branches Out",

abstract = "The branching of dendrites and axons is a key determinant of neural circuit formation. In this issue of Neuron, Kawabe et al. demonstrate that the ubiquitin ligase Nedd4 promotes the branching of developing dendrites by targeting the small G protein Rap2. In a complementary study, Drinjakovic et al. show that Nedd4 promotes the branching of developing axons by ubiquitinating a different target, the phosphatase PTEN.",

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N2 - The branching of dendrites and axons is a key determinant of neural circuit formation. In this issue of Neuron, Kawabe et al. demonstrate that the ubiquitin ligase Nedd4 promotes the branching of developing dendrites by targeting the small G protein Rap2. In a complementary study, Drinjakovic et al. show that Nedd4 promotes the branching of developing axons by ubiquitinating a different target, the phosphatase PTEN.

AB - The branching of dendrites and axons is a key determinant of neural circuit formation. In this issue of Neuron, Kawabe et al. demonstrate that the ubiquitin ligase Nedd4 promotes the branching of developing dendrites by targeting the small G protein Rap2. In a complementary study, Drinjakovic et al. show that Nedd4 promotes the branching of developing axons by ubiquitinating a different target, the phosphatase PTEN.

UR - https://www.scopus.com/pages/publications/75949118983

U2 - 10.1016/j.neuron.2010.01.028

DO - 10.1016/j.neuron.2010.01.028

M3 - Short survey

C2 - 20159442

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SN - 0896-6273

VL - 65

SP - 293

EP - 294

JO - Neuron

JF - Neuron

IS - 3

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Nedd4 Branches Out

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