Necrotic cell death: Harnessing the Dark side of the Force in mammary gland involution

Cliff J. Luke; Gary A. Silverman

doi:10.1038/ncb0311-197

Necrotic cell death: Harnessing the Dark side of the Force in mammary gland involution

Research output: Contribution to journal › Article › peer-review

Abstract

In response to major cellular insults, a massive increase in lysosomal membrane permeability (LMP) leads to necrosis. Data now reveal that this potent lysosomal-mediated necrotic cell-death machinery can also be harnessed for complex physiological processes, such as post-lactation mammary gland involution.

Original language	English
Pages (from-to)	197-199
Number of pages	3
Journal	Nature Cell Biology
Volume	13
Issue number	3
DOIs	https://doi.org/10.1038/ncb0311-197
State	Published - Mar 2011

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title = "Necrotic cell death: Harnessing the Dark side of the Force in mammary gland involution",

abstract = "In response to major cellular insults, a massive increase in lysosomal membrane permeability (LMP) leads to necrosis. Data now reveal that this potent lysosomal-mediated necrotic cell-death machinery can also be harnessed for complex physiological processes, such as post-lactation mammary gland involution.",

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AB - In response to major cellular insults, a massive increase in lysosomal membrane permeability (LMP) leads to necrosis. Data now reveal that this potent lysosomal-mediated necrotic cell-death machinery can also be harnessed for complex physiological processes, such as post-lactation mammary gland involution.

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Necrotic cell death: Harnessing the Dark side of the Force in mammary gland involution

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