Nature of tumor control by permanently and transiently modified GD2 chimeric antigen receptor T cells in xenograft models of neuroblastoma

Keyphrases

• Neuroblastoma 100%
• Chimeric Antigen Receptor T Cells (CAR-T) 100%
• Tumor Control 100%
• Xenograft Model 100%
• Disseminated Infection 37%
• T Cells 25%
• Histologic Examination 25%
• Long-term Disease 25%
• Disease Control 25%
• Modified Cells 25%
• Novel Treatments 12%
• Hematological Malignancies 12%
• Disease Model 12%
• Disease Response 12%
• Anti-tumor Response 12%
• Tumor Microenvironment 12%
• Improved Survival 12%
• T-cell Mediated 12%
• Tumor Environment 12%
• Long-term Control 12%
• Engineered Cells 12%
• Localized Disease 12%
• Pediatric Tumors 12%
• Disease Survival 12%
• In Vivo Bioluminescence 12%
• Tumor Measurement 12%
• Novel Antigens 12%
• NSG Mice 12%
• Xenograft Mice 12%
• Chimeric Antigen Receptor Therapy 12%
• Tumor Destruction 12%
• Xenograft Studies 12%
• MRNA Electroporation 12%

Medicine and Dentistry

• Neoplasm 100%
• Ganglioneuroblastoma 100%
• Xenograft 100%
• Chimeric Antigen Receptor T-Cell 100%
• Infusion 42%
• Disseminated Disease 42%
• Diseases 42%
• T Cell 28%
• Hematologic Malignancy 14%
• Receptor 14%
• Pediatrics 14%
• Immunotherapy 14%
• Solid Malignant Neoplasm 14%
• Disease Model 14%
• Tumor Microenvironment 14%
• Electroporation 14%
• Engineered Cell 14%
• Chimeric Antigen Receptor Immunotherapy 14%
• Bioluminescence 14%