TY - JOUR
T1 - Natural scenes viewing alters the dynamics of functional connectivity in the human brain
AU - Betti, Viviana
AU - DellaPenna, Stefania
AU - de Pasquale, Francesco
AU - Mantini, Dante
AU - Marzetti, Laura
AU - Romani, Gian Luca
AU - Corbetta, Maurizio
N1 - Funding Information:
This research was funded by the European Community’s Seventh Framework Programme Grant Agreement HEALTH-F2-2008-200728 (BrainSynch) and by the Human Connectome Project (1U54MH091657-01).V.B. was additionally supported by a fellowship from the University of Chieti. M.C. was supported by R01 MH096482-01 (NIMH) and 5R01HD061117-08 (NICHD).
PY - 2013/8/21
Y1 - 2013/8/21
N2 - Spontaneous fMRI fluctuations are organized in large-scale spatiotemporal structures, or resting-state networks (RSN). However, it is unknown how task performance affects RSN dynamics. We use MEG to measure slow (~0.1Hz) coherent fluctuations of band-limited power (BLP), a robust correlate of RSN, during rest and movie observation and compare them to fMRI-RSN. BLP correlation, especially in αband, dropped in multiple RSN during movie although overall topography was maintained. Variability of power correlation increased in visual occipital cortex, and transient decrements corresponded to scenes perceived as "event boundaries." Additionally, stronger task-dependent interactions developed between vision and language networks in θ and β bands, and default and language networks in γ band. The topography of fMRI connectivity and relative changes induced by the movie were well matched to MEG. We conclude that resting-state and task network interactions are clearly different in the frequency domain despite maintenance of underlying network topography
AB - Spontaneous fMRI fluctuations are organized in large-scale spatiotemporal structures, or resting-state networks (RSN). However, it is unknown how task performance affects RSN dynamics. We use MEG to measure slow (~0.1Hz) coherent fluctuations of band-limited power (BLP), a robust correlate of RSN, during rest and movie observation and compare them to fMRI-RSN. BLP correlation, especially in αband, dropped in multiple RSN during movie although overall topography was maintained. Variability of power correlation increased in visual occipital cortex, and transient decrements corresponded to scenes perceived as "event boundaries." Additionally, stronger task-dependent interactions developed between vision and language networks in θ and β bands, and default and language networks in γ band. The topography of fMRI connectivity and relative changes induced by the movie were well matched to MEG. We conclude that resting-state and task network interactions are clearly different in the frequency domain despite maintenance of underlying network topography
UR - http://www.scopus.com/inward/record.url?scp=84882638065&partnerID=8YFLogxK
U2 - 10.1016/j.neuron.2013.06.022
DO - 10.1016/j.neuron.2013.06.022
M3 - Article
C2 - 23891400
AN - SCOPUS:84882638065
VL - 79
SP - 782
EP - 797
JO - Neuron
JF - Neuron
SN - 0896-6273
IS - 4
ER -