Abstract
Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the innate immune system, and in particular natural killer (NK) cells, in stimulating or suppressing autoimmunity. This review focuses on recent research elucidating a potential immunoregulatory role for NK cells in modulating T and B cell-mediated autoimmunity.
| Original language | English |
|---|---|
| Pages (from-to) | 8-14 |
| Number of pages | 7 |
| Journal | Arthritis Research and Therapy |
| Volume | 6 |
| Issue number | 1 |
| State | Published - Feb 1 2004 |
Keywords
- Autoimmunity
- Immunoregulation
- Natural killer cells