Natural killer cell activation receptors in innate immunity to infection

Wayne M. Yokoyama; Anthony A. Scalzo

doi:10.1016/S1286-4579(02)00034-5

Natural killer cell activation receptors in innate immunity to infection

Wayne M. Yokoyama
, Anthony A. Scalzo

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

Natural killer (NK) cells are best known for their capacity to kill tumors but they are also critical in early innate responses to infection, especially herpesviruses. Recent studies indicate that NK cell receptors involved in tumor target specificity are also involved in responses to viral infections.

Original language	English
Pages (from-to)	1513-1521
Number of pages	9
Journal	Microbes and Infection
Volume	4
Issue number	15
DOIs	https://doi.org/10.1016/S1286-4579(02)00034-5
State	Published - Dec 2002

Keywords

Cytomegalovirus
Innate immunity
NK cells

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10.1016/S1286-4579(02)00034-5

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@article{e4e2b7d8ddb7405d82fbe29290136a8b,

title = "Natural killer cell activation receptors in innate immunity to infection",

abstract = "Natural killer (NK) cells are best known for their capacity to kill tumors but they are also critical in early innate responses to infection, especially herpesviruses. Recent studies indicate that NK cell receptors involved in tumor target specificity are also involved in responses to viral infections.",

keywords = "Cytomegalovirus, Innate immunity, NK cells",

author = "Yokoyama, \{Wayne M.\} and Scalzo, \{Anthony A.\}",

note = "Funding Information: The authors are grateful to members of their laboratories, past and present, who contributed over the last 12 years to the analysis and identification of Cmv1 and its mechanism of resistance. This manuscript is dedicated to them. Work in the Yokoyama laboratory is supported by the Howard Hughes Medical Institute, the Barnes-Jewish Hospital Research Foundation, and grants from the National Institutes of Health. A.A.S. is supported by grants 990646 and 139178 from the National Health and Medical Research Council of Australia.",

year = "2002",

month = dec,

doi = "10.1016/S1286-4579(02)00034-5",

language = "English",

volume = "4",

pages = "1513--1521",

journal = "Microbes and Infection",

issn = "1286-4579",

number = "15",

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TY - JOUR

T1 - Natural killer cell activation receptors in innate immunity to infection

AU - Yokoyama, Wayne M.

AU - Scalzo, Anthony A.

N1 - Funding Information: The authors are grateful to members of their laboratories, past and present, who contributed over the last 12 years to the analysis and identification of Cmv1 and its mechanism of resistance. This manuscript is dedicated to them. Work in the Yokoyama laboratory is supported by the Howard Hughes Medical Institute, the Barnes-Jewish Hospital Research Foundation, and grants from the National Institutes of Health. A.A.S. is supported by grants 990646 and 139178 from the National Health and Medical Research Council of Australia.

PY - 2002/12

Y1 - 2002/12

N2 - Natural killer (NK) cells are best known for their capacity to kill tumors but they are also critical in early innate responses to infection, especially herpesviruses. Recent studies indicate that NK cell receptors involved in tumor target specificity are also involved in responses to viral infections.

AB - Natural killer (NK) cells are best known for their capacity to kill tumors but they are also critical in early innate responses to infection, especially herpesviruses. Recent studies indicate that NK cell receptors involved in tumor target specificity are also involved in responses to viral infections.

KW - Cytomegalovirus

KW - Innate immunity

KW - NK cells

UR - https://www.scopus.com/pages/publications/0036927967

U2 - 10.1016/S1286-4579(02)00034-5

DO - 10.1016/S1286-4579(02)00034-5

M3 - Review article

C2 - 12505523

AN - SCOPUS:0036927967

SN - 1286-4579

VL - 4

SP - 1513

EP - 1521

JO - Microbes and Infection

JF - Microbes and Infection

IS - 15

ER -

Natural killer cell activation receptors in innate immunity to infection

Abstract

Keywords

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