Narrowing the spectrum: The new frontier of precision antimicrobials

Alexandra E. Paharik, Henry L. Schreiber, Caitlin N. Spaulding, Karen W. Dodson, Scott J. Hultgren

Research output: Contribution to journalComment/debate

10 Scopus citations


Antibiotics have become the standard of care for bacterial infections. However, rising rates of antibiotic-resistant infections are outpacing the development of new antimicrobials. Broad-spectrum antibiotics also harm beneficial microbial communities inhabiting humans. To combat antibiotic resistance and protect these communities, new precision antimicrobials must be engineered to target specific pathogens.

Original languageEnglish
Article number110
JournalGenome medicine
Issue number1
StatePublished - Dec 14 2017

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