Biomaterial scaffolds that present defined microenvironmental cues (e.g., nano-topography) to cells have shown promise for a variety of tissue engineering applications. However, the specific cues best suited for promoting the formation of aligned, fibrous tissues such as tendon are not fully understood. In this study, we utilize a microphotopatterning (μPP) model system to precisely arrange scaffoldmimicking microenvironmental cues and investigate their role in the formation of tendon-like neo-tissues. Our data show that scaffold architectural features at both nano- and micro- length scales may be important parameters for directing tendon-like cell organization and the formation of aligned, fibrillar collagen.

Original languageEnglish
Title of host publicationASME 2013 Summer Bioengineering Conference, SBC 2013
StatePublished - Dec 1 2013
EventASME 2013 Summer Bioengineering Conference, SBC 2013 - Sunriver, OR, United States
Duration: Jun 26 2013Jun 29 2013

Publication series

NameASME 2013 Summer Bioengineering Conference, SBC 2013
Volume1 B


ConferenceASME 2013 Summer Bioengineering Conference, SBC 2013
Country/TerritoryUnited States
CitySunriver, OR


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