N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: Synthesis, in vitro activity, and molecular modeling studies

Keyphrases

• In Vitro Activity 100%
• Caspase 100%
• Executor 100%
• Caspase-1 100%
• Activity Modeling 100%
• Molecular Modeling Studies 100%
• Caspase-3 Inhibitor 100%
• Inhibitor Synthesis 100%
• Sulfonamide Analog 100%
• N-alkylisatin 100%
• Apoptosis 50%
• Low Potencies 50%
• Caspase-3 50%
• Caspase-3 Activation 50%
• Nonapeptides 50%
• Caspase Inhibitor 50%
• Tissue Damage 50%
• Disease Conditions 50%
• Peptide-based 50%
• Caspase-7 50%
• Caspase-8 50%
• Isatin Sulfonamide 50%
• Caspase-6 50%
• Initiator Caspase 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Caspase 3 100%
• Sulfonamide 100%
• Caspase 100%
• Interleukin 1beta Converting Enzyme 100%
• Caspase 3 Inhibitor 100%
• Tissue Injury 50%
• Isatin 50%
• Caspase 7 50%
• Caspase Inhibitor 50%
• Caspase 6 50%
• Caspase 8 50%
• Initiator Caspase 50%
• Diseases 50%