TY - JOUR
T1 - Myofibroma of the mandible. Clinicopathologic study and review of the literature
AU - Sugatani, Toshifumi
AU - Inui, Madoka
AU - Tagawa, Toshiro
AU - Seki, Yutaka
AU - Mori, Atsusi
AU - Yoneda, Joji
PY - 1995/9
Y1 - 1995/9
N2 - A case of mandibular myofibroma in a 2-month-old boy is presented. Including this case, 24 pediatric and 11 adult patients with maxillofacial myofibroma have been reported since 1981. Of the 24 pediatric patients, 15 (62.5%) had lesions affecting the mandible. The adult cases had no mandibular involvement. Histologic evaluation of the tissue specimen revealed an interlacing pattern of spindle-shaped cells with long oval nuclei. Tissue immunohistochemical staining found it to be reactive for antibodies directed against vimentin and α-smooth muscle actin, but not desmin, S-100 protein, neuron-specific enolase, or myoglobin. Electron microscopy examination revealed the following cells: myofibroblast-like cells, fibroblast-like cells, and intermediate cells that were similar to the fibroblast-like cells except for the presence of a few microfilaments. Myoblast-like cells were not seen.
AB - A case of mandibular myofibroma in a 2-month-old boy is presented. Including this case, 24 pediatric and 11 adult patients with maxillofacial myofibroma have been reported since 1981. Of the 24 pediatric patients, 15 (62.5%) had lesions affecting the mandible. The adult cases had no mandibular involvement. Histologic evaluation of the tissue specimen revealed an interlacing pattern of spindle-shaped cells with long oval nuclei. Tissue immunohistochemical staining found it to be reactive for antibodies directed against vimentin and α-smooth muscle actin, but not desmin, S-100 protein, neuron-specific enolase, or myoglobin. Electron microscopy examination revealed the following cells: myofibroblast-like cells, fibroblast-like cells, and intermediate cells that were similar to the fibroblast-like cells except for the presence of a few microfilaments. Myoblast-like cells were not seen.
UR - http://www.scopus.com/inward/record.url?scp=0029365530&partnerID=8YFLogxK
U2 - 10.1016/S1079-2104(05)80388-9
DO - 10.1016/S1079-2104(05)80388-9
M3 - Article
C2 - 7489274
AN - SCOPUS:0029365530
SN - 1079-2104
VL - 80
SP - 303
EP - 309
JO - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and
JF - Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and
IS - 3
ER -