TY - JOUR
T1 - Myocardial ischaemia after hip and knee arthroplasty
T2 - incidence and risk factors
AU - Bass, Anne Ruth
AU - Rodriguez, Tomás
AU - Hyun, Gina
AU - Santiago, Francisco Gerardo
AU - Kim, Jacqueline Ilji
AU - Woller, Scott Christopher
AU - Gage, Brian Foster
N1 - Publisher Copyright:
© 2015, SICOT aisbl.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2015/10/26
Y1 - 2015/10/26
N2 - Purpose: Because the occurrence of postoperative myocardial ischaemia (MI) predicts subsequent cardiac morbidity and mortality, we determined the prevalence of and risk factors for MI in hip and knee arthroplasty patients. Methods: High-sensitivity cardiac troponin T (hs-cTnT) was measured on stored samples from postoperative day two in 394 hip and knee arthroplasty patients ≥ 65 years of age enrolled in the Genetics-InFormatics Trial (GIFT). Results: Fifty-three (13.5 %) participants had MI, of whom only three were diagnosed clinically during their hospitalisation. The risk of MI increased with age [odds ratio (OR) 3.52 per decade, 95 % confidence interval (CI) 2.00–6.19] and diabetes (OR 2.23, 95 % CI 1.04–4.77). MI was rarer with statins (OR 0.74, 95 % CI 0.40–1.35) and more common with hypertension, coronary artery disease and tobacco use, although these were not statistically significant. Conclusions: Subclinical MI occurs frequently after arthroplasty. Diabetic and elderly patients are at highest risk.
AB - Purpose: Because the occurrence of postoperative myocardial ischaemia (MI) predicts subsequent cardiac morbidity and mortality, we determined the prevalence of and risk factors for MI in hip and knee arthroplasty patients. Methods: High-sensitivity cardiac troponin T (hs-cTnT) was measured on stored samples from postoperative day two in 394 hip and knee arthroplasty patients ≥ 65 years of age enrolled in the Genetics-InFormatics Trial (GIFT). Results: Fifty-three (13.5 %) participants had MI, of whom only three were diagnosed clinically during their hospitalisation. The risk of MI increased with age [odds ratio (OR) 3.52 per decade, 95 % confidence interval (CI) 2.00–6.19] and diabetes (OR 2.23, 95 % CI 1.04–4.77). MI was rarer with statins (OR 0.74, 95 % CI 0.40–1.35) and more common with hypertension, coronary artery disease and tobacco use, although these were not statistically significant. Conclusions: Subclinical MI occurs frequently after arthroplasty. Diabetic and elderly patients are at highest risk.
KW - Arthroplasty
KW - Myocardial ischaemia
KW - Postoperative complication
KW - Risk factor
KW - Statin
KW - Troponin
UR - http://www.scopus.com/inward/record.url?scp=84942292496&partnerID=8YFLogxK
U2 - 10.1007/s00264-015-2853-0
DO - 10.1007/s00264-015-2853-0
M3 - Article
C2 - 26156715
AN - SCOPUS:84942292496
VL - 39
SP - 2011
EP - 2016
JO - International Orthopaedics
JF - International Orthopaedics
SN - 0341-2695
IS - 10
ER -