Myocardial Blood Volume Is Associated With Myocardial Oxygen Consumption. An Experimental Study With Cardiac Magnetic Resonance in a Canine Model

Kyle S. McCommis, Haosen Zhang, Thomas A. Goldstein, Bernd Misselwitz, Dana R. Abendschein, Robert J. Gropler, Jie Zheng

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Understanding the oxygen consumption of the left ventricular myocardium provides important insight into the relationship between myocardial oxygen supply and demand. In other territories, cardiac magnetic resonance has been utilized to measure myocardial oxygen consumption with a blood level oxygen dependent (BOLD) technique. The BOLD technology requires repetitive sampling of stationary tissues and is frequently implemented in areas such as the brain. A limitation to utilizing BOLD cardiac magnetic resonance techniques in the heart has been cardiac motion. In this study, we document a methodology for acquiring BOLD images in the heart and demonstrate the utility of the technique for identifying associations between myocardial oxygen consumption and blood flow.

Original languageEnglish
Pages (from-to)1313-1320
Number of pages8
JournalJACC: Cardiovascular Imaging
Volume2
Issue number11
DOIs
StatePublished - Nov 2009

Keywords

  • blood oxygen level dependent
  • cardiac magnetic resonance
  • myocardial blood flow
  • myocardial blood volume
  • myocardial oxygen consumption

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