Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling

Daniel A. Pollyea; Chelsea Harris; Jennifer L. Rabe; Brenna R. Hedin; Lesly De Arras; Sigrid Katz; Emily Wheeler; Rafael Bejar; Matthew J. Walter; Craig T. Jordan; Eric M. Pietras; Scott Alper

doi:10.3324/haematol.2018.214155

Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling

Daniel A. Pollyea, Chelsea Harris, Jennifer L. Rabe, Brenna R. Hedin, Lesly De Arras, Sigrid Katz, Emily Wheeler, Rafael Bejar, Matthew J. Walter, Craig T. Jordan, Eric M. Pietras, Scott Alper

Research output: Contribution to journal › Letter › peer-review

44 Scopus citations

Original language	English
Pages (from-to)	E388-E392
Journal	Haematologica
Volume	104
Issue number	9
DOIs	https://doi.org/10.3324/haematol.2018.214155
State	Published - Aug 31 2019

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10.3324/haematol.2018.214155

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@article{0b39de216056494e81108719b43ea401,

title = "Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling",

author = "Pollyea, {Daniel A.} and Chelsea Harris and Rabe, {Jennifer L.} and Hedin, {Brenna R.} and {De Arras}, Lesly and Sigrid Katz and Emily Wheeler and Rafael Bejar and Walter, {Matthew J.} and Jordan, {Craig T.} and Pietras, {Eric M.} and Scott Alper",

note = "Funding Information: Funding: this study was supported by National Institutes of Health grants R01ES025161 (to SA), K01DK098315 (to EMP), F31HL138754 (to JLR), the V Foundation Scholar Award (to RB) as well as grants from the Cancer League of Colorado, the University of Colorado Hematological Malignancies Pilot Grant Program, University of Colorado RNA Biosciences Initiative Project Grant, and the Wendy Siegel Fund for Leukemia and Cancer Research. CTJ is generously supported by the Nancy Carroll Allen Chair in Hematology Research. DAP is a Leukemia and Lymphoma Society Scholar in Clinical Research. Acknowledgments: thanks to Matthew Meyerson, Cara Lunn Shirai, and Peter Sporn for providing assistance and reagents. Correspondence: SCOTT ALPER - [email protected]. doi:10.3324/haematol.2018.214155 Information on authorship, contributions, and financial & other disclosures was provided by the authors and is available with the online version of this article at www.haematologica.org.",

year = "2019",

month = aug,

day = "31",

doi = "10.3324/haematol.2018.214155",

language = "English",

volume = "104",

pages = "E388--E392",

journal = "Haematologica",

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TY - JOUR

T1 - Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling

AU - Pollyea, Daniel A.

AU - Harris, Chelsea

AU - Rabe, Jennifer L.

AU - Hedin, Brenna R.

AU - De Arras, Lesly

AU - Katz, Sigrid

AU - Wheeler, Emily

AU - Bejar, Rafael

AU - Walter, Matthew J.

AU - Jordan, Craig T.

AU - Pietras, Eric M.

AU - Alper, Scott

N1 - Funding Information: Funding: this study was supported by National Institutes of Health grants R01ES025161 (to SA), K01DK098315 (to EMP), F31HL138754 (to JLR), the V Foundation Scholar Award (to RB) as well as grants from the Cancer League of Colorado, the University of Colorado Hematological Malignancies Pilot Grant Program, University of Colorado RNA Biosciences Initiative Project Grant, and the Wendy Siegel Fund for Leukemia and Cancer Research. CTJ is generously supported by the Nancy Carroll Allen Chair in Hematology Research. DAP is a Leukemia and Lymphoma Society Scholar in Clinical Research. Acknowledgments: thanks to Matthew Meyerson, Cara Lunn Shirai, and Peter Sporn for providing assistance and reagents. Correspondence: SCOTT ALPER - [email protected]. doi:10.3324/haematol.2018.214155 Information on authorship, contributions, and financial & other disclosures was provided by the authors and is available with the online version of this article at www.haematologica.org.

PY - 2019/8/31

Y1 - 2019/8/31

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U2 - 10.3324/haematol.2018.214155

DO - 10.3324/haematol.2018.214155

M3 - Letter

C2 - 30846499

AN - SCOPUS:85071784909

SN - 0390-6078

VL - 104

SP - E388-E392

JO - Haematologica

JF - Haematologica

IS - 9

ER -

Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling

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