Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy

Eric J. Duncavage; Geoffrey L. Uy; Allegra A. Petti; Christopher A. Miller; Yi Shan Lee; Bevan Tandon; Feng Gao; Catrina C. Fronick; Michelle O'Laughlin; Robert S. Fulton; Richard K. Wilson; Meagan A. Jacoby; Amanda F. Cashen; Lukas D. Wartman; Matthew J. Walter; Peter Westervelt; Daniel C. Link; John F. DiPersio; Timothy J. Ley; John S. Welch

doi:10.1182/blood-2016-10-745273

Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy

Eric J. Duncavage, Geoffrey L. Uy, Allegra A. Petti, Christopher A. Miller, Yi Shan Lee, Bevan Tandon, Feng Gao, Catrina C. Fronick, Michelle O'Laughlin, Robert S. Fulton, Richard K. Wilson, Meagan A. Jacoby, Amanda F. Cashen, Lukas D. Wartman, Matthew J. Walter, Peter Westervelt, Daniel C. Link, John F. DiPersio, Timothy J. Ley, John S. Welch

Research output: Contribution to journal › Letter › peer-review

23 Scopus citations

Original language	English
Pages (from-to)	1397-1401
Number of pages	5
Journal	Blood
Volume	129
Issue number	10
DOIs	https://doi.org/10.1182/blood-2016-10-745273
State	Published - Mar 9 2017

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Duncavage, E. J., Uy, G. L., Petti, A. A., Miller, C. A., Lee, Y. S., Tandon, B., Gao, F., Fronick, C. C., O'Laughlin, M., Fulton, R. S., Wilson, R. K., Jacoby, M. A., Cashen, A. F., Wartman, L. D., Walter, M. J., Westervelt, P., Link, D. C., DiPersio, J. F., Ley, T. J., & Welch, J. S. (2017). Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy. Blood, 129(10), 1397-1401. https://doi.org/10.1182/blood-2016-10-745273

@article{92985365e0214827aa4e6635c8f99a28,

title = "Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy",

author = "Duncavage, {Eric J.} and Uy, {Geoffrey L.} and Petti, {Allegra A.} and Miller, {Christopher A.} and Lee, {Yi Shan} and Bevan Tandon and Feng Gao and Fronick, {Catrina C.} and Michelle O'Laughlin and Fulton, {Robert S.} and Wilson, {Richard K.} and Jacoby, {Meagan A.} and Cashen, {Amanda F.} and Wartman, {Lukas D.} and Walter, {Matthew J.} and Peter Westervelt and Link, {Daniel C.} and DiPersio, {John F.} and Ley, {Timothy J.} and Welch, {John S.}",

note = "Funding Information: The authors thank Greg Malnassy, Nichole Helton, and the Washington University Tissue Procurement Core for sample storage and sample preparation, and Theresa Fletcher, Megan Haney, Shannon Kramer, Sharon Heath, Kierstin Luber, Megan Janke, and Paige Schnoebelen for assistance in patient enrollment, sample collection, and clinical data processing. This work was supported by a National Institutes of Health National Cancer Institute Acute Myeloid Leukemia (AML)-Specialized Programs of Research Excellence (P50 CA171963), the Genomics of AML Program Project grant (P01 CA101937), and the Alliance for Clinical Trials in Oncology Foundation (G.L.U.).",

year = "2017",

month = mar,

day = "9",

doi = "10.1182/blood-2016-10-745273",

language = "English",

volume = "129",

pages = "1397--1401",

journal = "Blood",

issn = "0006-4971",

number = "10",

}

Duncavage, EJ , Uy, GL, Petti, AA, Miller, CA , Lee, YS, Tandon, B, Gao, F, Fronick, CC, O'Laughlin, M, Fulton, RS, Wilson, RK, Jacoby, MA , Cashen, AF, Wartman, LD, Walter, MJ, Westervelt, P, Link, DC , DiPersio, JF , Ley, TJ & Welch, JS 2017, 'Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy', Blood, vol. 129, no. 10, pp. 1397-1401. https://doi.org/10.1182/blood-2016-10-745273

TY - JOUR

T1 - Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy

AU - Duncavage, Eric J.

AU - Uy, Geoffrey L.

AU - Petti, Allegra A.

AU - Miller, Christopher A.

AU - Lee, Yi Shan

AU - Tandon, Bevan

AU - Gao, Feng

AU - Fronick, Catrina C.

AU - O'Laughlin, Michelle

AU - Fulton, Robert S.

AU - Wilson, Richard K.

AU - Jacoby, Meagan A.

AU - Cashen, Amanda F.

AU - Wartman, Lukas D.

AU - Walter, Matthew J.

AU - Westervelt, Peter

AU - Link, Daniel C.

AU - DiPersio, John F.

AU - Ley, Timothy J.

AU - Welch, John S.

N1 - Funding Information: The authors thank Greg Malnassy, Nichole Helton, and the Washington University Tissue Procurement Core for sample storage and sample preparation, and Theresa Fletcher, Megan Haney, Shannon Kramer, Sharon Heath, Kierstin Luber, Megan Janke, and Paige Schnoebelen for assistance in patient enrollment, sample collection, and clinical data processing. This work was supported by a National Institutes of Health National Cancer Institute Acute Myeloid Leukemia (AML)-Specialized Programs of Research Excellence (P50 CA171963), the Genomics of AML Program Project grant (P01 CA101937), and the Alliance for Clinical Trials in Oncology Foundation (G.L.U.).

PY - 2017/3/9

Y1 - 2017/3/9

UR - http://www.scopus.com/inward/record.url?scp=85015152527&partnerID=8YFLogxK

U2 - 10.1182/blood-2016-10-745273

DO - 10.1182/blood-2016-10-745273

M3 - Letter

C2 - 28082444

AN - SCOPUS:85015152527

SN - 0006-4971

VL - 129

SP - 1397

EP - 1401

JO - Blood

JF - Blood

IS - 10

ER -

Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy

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