Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: Evidence for augmentation of a 42-specific γ secretase

  • Joanna L. Jankowsky
  • , Daniel J. Fadale
  • , Jeffrey Anderson
  • , Guilian M. Xu
  • , Victoria Gonzales
  • , Nancy A. Jenkins
  • , Neal G. Copeland
  • , Michael K. Lee
  • , Linda H. Younkin
  • , Steven L. Wagner
  • , Steven G. Younkin
  • , David R. Borchelt

Research output: Contribution to journalReview articlepeer-review

1361 Scopus citations

Fingerprint

Dive into the research topics of 'Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: Evidence for augmentation of a 42-specific γ secretase'. Together they form a unique fingerprint.

Keyphrases

Neuroscience

Biochemistry, Genetics and Molecular Biology