Musculoskeletal models with generic and subject-specific geometry estimate different joint biomechanics in dysplastic hips

Ke Song, Andrew E. Anderson, Jeffrey A. Weiss, Michael D. Harris

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Optimizing the geometric complexity of musculoskeletal models is important for reliable yet feasible estimation of joint biomechanics. This study investigated the effects of subject-specific model geometry on hip joint reaction forces (JRFs) and muscle forces in patients with developmental dysplasia of the hip (DDH) and healthy controls. For nine DDH and nine control subjects, three models were created with increasingly subject-specific pelvis geometry, hip joint center locations and muscle attachments. Hip JRFs and muscle forces during a gait cycle were compared among the models. For DDH subjects, resultant JRFs from highly specific models including subject-specific pelvis geometry, joint locations and muscle attachments were not significantly different compared to models using generic geometry in early stance, but were significantly higher in late stance (p = 0.03). Estimates from moderately specific models using CT-informed scaling of generic pelvis geometry were not significantly different from low specificity models using generic geometry scaled with skin markers. For controls, resultant JRFs in early stance from highly specific models were significantly lower than moderate and low specificity models (p ≤ 0.02) with no significant differences in late stance. Inter-model JRF differences were larger for DDH subjects than controls. Inter-model differences for JRF components and muscle forces were similar to resultant JRFs. Incorporating subject-specific pelvis geometry significantly affects JRF and muscle force estimates in both DDH and control groups, which may be especially important for reliable estimation of pathomechanics in dysplastic hips.

Original languageEnglish
Pages (from-to)259-270
Number of pages12
JournalComputer Methods in Biomechanics and Biomedical Engineering
Issue number3
StatePublished - Feb 17 2019


  • Musculoskeletal modeling
  • biomechanics
  • developmental dysplasia of the hip
  • hip
  • joint reaction force
  • subject-specific

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