Natural killer (NK) cells express two types of receptors involved in target recognition: inhibitory receptors for target cell MHC class I molecules and activation receptors. While there has been significant progress in understanding the inhibitory receptors, less is known about the activation receptors. Detailed analysis of several mouse NK-cell activation receptors provides insight into the physiologic relevance of these receptors in the innate immune response.

Original languageEnglish
Pages (from-to)115-125
Number of pages11
JournalImmunological Reviews
StatePublished - Aug 14 2001


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