@inproceedings{05ed174d1daf4ae0aaab5700d5248a5e,
title = "Multiscale imaging of human thyroid pathologies using integrated Optical Coherence Tomography (OCT) and Optical Coherence Microscopy (OCM)",
abstract = "We evaluate the feasibility of optical coherence tomography (OCT) and optical coherence microscopy (OCM) for imaging of benign and malignant thyroid lesions ex vivo using intrinsic optical contrast. Thirty four thyroid gland specimens were imaged from 17 patients, covering a spectrum of pathology, ranging from normal thyroid to neoplasia and benign disease. The integrated OCT and OCM imaging system allows seamlessly switching between low and high magnifications, in a way similar to traditional microscopy. Good correspondence was observed between optical images and histological sections. The results provide a basis for interpretation of future OCT and OCM images of the thyroid tissues and suggest the possibility of future in vivo evaluation of thyroid pathology.",
keywords = "Cancer, Optical Coherence Microscopy (OCM), Optical Coherence Tomography (OCT), Pathology, Thyroid",
author = "Chao Zhou and Yihong Wang and Aguirre, {Aaron D.} and Tsai, {Tsung Han} and Cohen, {David W.} and Connolly, {James L.} and Fujimoto, {James G.}",
year = "2010",
doi = "10.1117/12.843616",
language = "English",
isbn = "9780819479501",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV",
note = "Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV ; Conference date: 25-01-2010 Through 27-01-2010",
}